Sample Handling

Proper identification of specimens is extremely important. Please confirm that all specimens are labeled with specimen labels from the Test Request Form for each patient. Specimen labels are unique and specific only to each individual patient.

• HERmark™ Breast Cancer Assay requires formalin-fixed, paraf in-embedded (FFPE) tissue.
• Invasive adenocarcinoma of breast is required; DCIS and LCIS only cases are not acceptable.
• Excisional biopsy specimens are preferred; large core biopsies are also acceptable.

Please send either:

• Unstained slides
• 5-μm sections on positively charged glass slides, 1 section per slide. A total of 5 unstained slides per patient is required.
• Freshly cut sections, stored at 4ºC, should be sent to Monogram Biosciences within 1 week.

OR

• 1 paraffin-embedded tissue block
• If multiple blocks are available, select the tissue block with the highest amount of viable invasive tumor - submit only one block.